Butyrate is an amino acid that is created by bacteria that live in the colon (the butyric acid) and it is this compound that is responsible for the leaky gut syndrome. The gut (colon) is a critical part of the human body. In the small intestine there are trillions of bacteria that break down proteins, fats and carbohydrates. If these bacteria were not present in the human body would be unable to produce these enzymes due to their high protein requirements.

Bacteria in the colon release butyrate as a byproduct of their digestive work. This chemical however is very volatile and will easily escape back into the blood stream when it is broken down. This will then activate other bacteria which will also release butyrate into the bloodstream, bringing it back to the site of action. This constant chain reaction then leads to the stomach producing a series of acids to wash away excess butyrate from the blood stream.

This process can result in serious adverse effects such as ulcers and peptic ulcers. It is thought however that butyrate leaks through the top layers of the skin causing allergic reactions in those who are sensitive to it. To combat the problem of butyrate leaky gut syndrome, it is important to keep the colon healthy by eating a well-balanced diet full of fibre and butyrate rich foods. Some of the more obvious causes of butyrate being released into the bloodstream include food processing, food storage, meat and fish processing as well as dietary supplements.

To prevent butyrate from leaking into the blood stream, it is recommended that these items are not eaten raw or cooked, but instead should be cooked or added to food immediately. Also, it is best to avoid any food or dietary supplement that contains butyrate as this will also be an invitation to butyrate leaky gut syndrome.